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Contrave diet pill is one of the newest weight-loss drugs that are now available by prescription in the United States.



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Contrave diet pill is one of the newest weight-loss drugs that are now available by prescription in the United States. The medication is a combination of two already existing FDA approved drugs (Bupropion and Naltrexone). The drug was developed by the American pharmaceutical company Orexigen Therapeutics. Over seven thousand prescriptions were written for this promising new medication just in the first week of becoming available on the market.

Contravening ER was proven to be effective during several randomized clinical trials. In order to qualify as a weight loss medication in the United States, the drug should make patients lose at least 5 percent of their body weight over a set period of time.

The participants in the trials had to maintain a low-calorie diet, lead a more active lifestyle, including more exercise to their daily routines and were either given Contrave diet pills or placebo.

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Contrave contains a combination of bupropion and naltrexone. Bupropion is an antidepressant medication that can also decrease appetite. Naltrexone is usually given to block the effects of narcotics or alcohol in people with addiction problems. Naltrexone may also curb hunger and food cravings. Contrave is anorexiant and is used to help manage weight in obese or overweight adults with weight-related medical problems. Contrave will not treat any weight-related medical conditions, such as high blood pressure, diabetes, or high cholesterol. It is not approved to treat depression or other psychiatric conditions, or to help you quit smoking. 
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Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life.

Naltrexone belongs to a class of drugs known as opiate antagonists, and bupropion is an antidepressant that may help restore the balance of certain natural chemicals (neurotransmitters) in your brain. These two medications work together on separate parts of the brain to reduce appetite and how much you eat.

 Ask your doctor or pharmacist for more details.

Discuss the risks and benefits of this medication, as well as other ways to lose weight, with your doctor.

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  • Read the Medication Guide is available from your pharmacist before you start taking naltrexone/bupropion and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
  • Take this medication by mouth with a low-fat meal as directed by your doctor, usually twice daily.
  • You may have trouble sleeping when you start taking this drug. Do not take your evening dose too close to bedtime.
  • Swallow the tablets whole. Do not crush or chew this medication. Doing so can release all of the drugs at once, increasing the risk of side effects such as seizures.
  • The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Do not increase your dose, take it more often, or stop taking it without your doctor’s approval.
  • Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Tell your doctor if you have not lost weight after 16 weeks on this medication.

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